(Big Pharma, it Should be noted, is the Untrustworthy, Unindicted Criminal Cartel that Brought us the Opioid Crisis)

This article explains, at least partially, the steadily enlarging numbers of learning disabled, intellectually-disabled, behaviorally-disordered, autism spectrum disordered children that come out of the large populations of fully vaccinated (and therefore over-vaccinated) infants and children (with thimerosal/mercury brain toxicity syndromes and/or aluminum adjuvanted vaccine-induced toxic encephalopathies and/or live vaccine virus-induced measles infectious encephalopathies.

 

These poor Big Pharma/Big Medicine corporation-damaged kids are now mostly chronically ill, over-medicated children that never made it past pre-school and are now institutionalized or ”living” at “home” under their parent’s 24 hour care-giving (80% of those parents get divorced due to the extreme stress).

 

The statistics-based predictions are that, if the over-vaccinating of America’s children with neurotoxic and autoimmunity-inducing vaccine ingredients doesn’t dramativally decrease soon, the incidence of autism among America’s fully-vaccinated children will approach 50% within the decade! 

 

To those of us who are seeing the steady drift towards racism, cruelty, militarism, totalitarianism, male supremacy and fascism in the world, a cost-efficient euthanasia movement could emerge that might eventually justify a right-wing, state-sponsored program similar to the one that Nazi Germany directed against the mentally and physically disabled but which the Nazis pretended was operated “out of compasson for those who lived lives unworthy of life”.

 

American soldiers are trained to be unconditionally obedient to authorities - no matter what - and they would do what they are ordered to do, whether the order was legal or for enforcing vaccinations (like in Brooklyn) or making arrests of non-violent dissidents who embarrassed America by revealing its war crimes (by exposing its international war criminals - like Julian Assange). I know that many Nazi soldiers were as reluctant to obey orders from above, as are any nation’s soldiers, including America’s. Discuss.

GGK

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Duty to Warn

 

A Few Important Questions that Parents need to Ponder Before They Consent to Allowing their Baby to be Inoculated with the Next Round of Big Pharma Recommended Vaccinations

 

(Big Pharma, it Should be noted, is the Untrustworthy, Unindicted Criminal Cartel that Brought us the Opioid Crisis)

 

By Gary G. Kohls, MD – April 13, 2019 (1,145 + abstracts 2,805 = 3,950 words)

 

No photo description available.

 

There are a few important questions that all parents of “vaccine-eligible” infants and children must ask before they allow their children to get the next CDC-recommended round of (over) vaccinations. Most parents have been prevented from hearing or reading the necessary information that would naturally make them “hesitant” to allow their children to be injected with obviously toxic and autoimmunity-inducing inoculations. 

 

Those of us in the Anti-Over-Vaccination Resistance Movement have apparently been “too effective” (for Big Pharma’s tastes) in proving to logical folks that over-vaccinating infants and children with toxic or auto-immunity disorder-inducing vaccines isn’t a good idea.

 

Apparently our sound science-based writings, lectures, videos and conferences have too-effectively refuted what the for-profit corporations that make up Big Pharma, Big Medicine, Big Government, Big Media and Wall Street that have been trying to indoctrinate everybody into trusting: that 100% of vaccines are 100% safe, 100%: effective and 100% necessary (all lies).

 

All of our efforts at truth-telling are being increasingly censored by recent “book-burnings” by social media entities (like Face Book, YouTube, Pinterest, Amazon, etc) that have, via threats by US governmental agencies – with the eager assistance from their cohorts in Big Pharma and Big Medicine, prohibited truth-telling efforts that they can’t disprove. And so, as always happens when propaganda fails to convince prospective customers, libel, ridicule and name-calling are used against the truth-tellers who are pointing out why “vaccine hesitancy” makes total sense..

 

(BTW, the large corporations that are in the above groups all meet the definition of “sociopathic entities” that routinely lie and therefore cannot be trusted.)

 

Question #1: Have you or anybody that you have heard about ever experienced post-vaccination complaints of any of the following short list of symptoms?

Myalgia (muscle pain), myositis, muscle weakness, arthralgia (joint pain), arthritis, chronic fatigue, sleep disturbances, cognitive impairment, chronic headache or memory loss. (The onset of these symptoms may have been either acute or delayed by weeks or months after the inoculations. Note that this is just a short list of autoimmune symptoms and signs.)

 

Question # 2: Do you know any fully vaccinated people that have suffered any of the following disorders that easily may represent undiagnosed, preventable, iatrogenic, aluminum-adjuvanted, vaccine-induced autoimmune disorders? (Note that a failure to accurately diagnose the cause of vaccine-induced disorders will invariably mean that the treatment – and future prevention as well - will be erroneous.)

Rheumatoid arthritis (RA), diabetes mellitus (type 1), Systemic Lupus Erythematosis (SLE), demyelinating neurological disorders such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Idiopathic Thrombocytopenic Purpura (ITP), vasculitis, dermatomyositis, Guillain-Barre Syndrome (GBS), Alzheimer’s Dementia (AD), Gulf War Syndrome (GWS), Macrophagic Myofasciitis Syndrome (MMF), Autism Spectrum Disorders (ASD), Primary Biliary Cirrhosis (PBC), Autoimmune Thyroid Diseases (AITD), Addisonian crisis and thyroid storm, ASIA, et, etc.

 

Question # 3: Wouldn’t you as a parent prefer having your child go through a benign and transient viral illness such as measles, mumps, rubella or chicken pox (illnesses that would actually give them life-long immunity with never any need for booster shots [as opposed to fully vaccinated children that will “need” to be re-vaccinated over and over again to just maintain their theoretical partial serological immunity])?

 

Question #4: Or are you as a parent willing to take the very serious risk of causing your child to come down with (for example):vaccine-induced sudden infant death syndrome (SIDS), near-SIDS, Guillain-Barre Syndrome, vaccine-induced encephalopathy, vaccine-induced neurodevelopmental disorders, vaccine-induced learning disorders, an autism spectrum disorder, so-called attention/hyperactivity disorder (ADHD), aluminum adjuvant-induced diabetes mellitus type 1, transverse myelitis, multiple sclerosis or any of the many other life-long, chronic, aluminum-adjuvant-induced autoimmune disorders listed above and below that could cause your child to be a chronically ill, permanent patient that will be dependent on medical care for the rest of his/her life?

 

The level of alarm that should be generated as you try to respond to the above questions will reveal how mis-informed and even dis-informed you and your physicians have become, thanks to the profit-motivated entities within Big Pharma and Big Medicine (including the AAP, the AMA, the AAFP, the CDC, the FDA and the NIH).

 

Consider this statement concerning the many still-unrecognized contraindications that should have been instituted years ago prohibiting some future vaccinations in certain cases. It comes from Dr Yehuda Shoenfeld, the “Godfather of Autoinnumology”):

 

“It seems preferable that individuals with prior autoimmune or autoimmune-like reactions to vaccinations, should not be immunized, at least not with the same type of vaccine.”

 

“Whoever Pays the Piper, Calls the Tune.”

 

Big Media, which derives 70% of its revenues from Big Pharma direct-to-consumer advertising has been in cahoots with Big Pharma in creating the web of lies and disinformation. This incestuous relationship has effectively silenced reporters, journalists and columnists, thus keeping them from doing open and honest investigative journalism,

 

Aluminum-adjuvant-induced autoimmune disorders can induce a variety of signs and symptoms beyond those listed above. Most physicians, indoctrinated from the time of their medical school propagandizing that led them to falsely believe that all vaccines are safe, will therefore not recognize the cause of these vaccine-induced disorders and therefore they will be blind to the treatment and ignorantly miss the chance to prevent future recurrences of the disorders.

 

In addition, some individuals (not just children) who have been injected with live virus vaccines (such as MMR-II (measles, mumps, rubella), varicella (chickenpox), influenza (nasal spray) and rotavirus are known to be contagious to close contacts (as in schools) for weeks or months.

 

An unknown percentage of recently-vaccinated individuals will be fully capable of contagiously shedding vaccine-viruses to their contacts (many of whom are fully vaccinated but are still not immune from the so-called/erroneously-labeled, “vaccine-preventable” diseases) are then capable of causing mini-epidemics of measles or mumps in classrooms, churches, neighborhoods, movie theaters, the shopping mall or Disney Land.

 

In other words, children who have been recently vaccinated with Merck & Company’s MMR II vaccine should be the ones who are targeted by public health authorities or mayor’s offices for forcible quarantine from public spaces and NOT the healthy, innocent, unvaccinated children who have no signs or symptoms of a viral illness!

 

<<<Vaccination is NOT the Same as Immunization>>>

 

Of course Big Pharma uses such episodes as scare-mongering propaganda opportunities to urge everybody to get their booster shots. Big Pharma uses its Big Media and Big Medicine cohorts to illogically blame the un-vaccinated rather than logically blaming the fully-vaccinated as being the root cause of the mini-epidemic. One of the big problems is that being full-vaccinated with some Big Pharma virus vaccine product does not necessarily mean that you are immune to viral illnesses caused by that virus

 

Toxic reactions to some of the other substances that are present in vaccines and injected intramuscularly (besides aluminum and mercury) are cumulative. Read the following articles that strongly support the above notion. Gary G. Kohls, MD

 

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Rom J Intern Med. 2013 Jul-Dec;51(3-4):131-4.

ASIA or Shoenfeld's syndrome--an autoimmune syndrome induced by adjuvants.

Cojocaru MChicoş B.

https://www.ncbi.nlm.nih.gov/pubmed/24620624

Abstract

Recently, reports have suggested grouping different autoimmune conditions that are triggered by external stimuli as a single syndrome called autoimmune syndrome induced by adjuvants (ASIA). This syndrome is characterized by the appearance of myalgia, myositis, muscle weakness, arthralgia, arthritis, chronic fatigue, sleep disturbances, cognitive impairment and memory loss, and the possible emergence of a demyelinating autoimmune disease caused by systemic exposure after vaccines and adjuvants. As there are no markers for ASIA, the authors intend to present ASIA, or Shoenfeld's syndrome, as an autoimmune syndrome induced by adjuvants.

 

 

Yehuda Shoenfeld: Top Israeli Doctor Points to Vaccines as Contributing to the Rising Rate of Autoimmune Diseases

 

https://www.shebaonline.org/top-israeli-doctor-points-vaccines-contributing-rising-rate-autoimmune-diseases/

 

Dr Shoenfeld (nicknamed the “Godfather of Autoimmunology”) recently published an article in Pharmacological Research that explores how vaccines may be contributing to the growing epidemic of autoimmune diseases. The article is based on massive amounts of research that have been accumulating over the past 15 years.

 

Dr. Shoenfeld is the founder and head of the Zabludowicz Center for Autoimmune Diseases at Sheba Medical Center. He is also the editor of three medical journals and has authored over 1,500 research papers across the spectrum of medical journalism. In addition, he is the founder of the International Congress of Autoimmunity.

 

As his many accomplishments attest, Dr. Shoenfeld is regarded as a mainstream medical specialist, and is by no means a fringe doctor. In fact, he wrote 25 classic textbooks on the human immune system, such as The Mosaic of Autoimmunity, Autoantibodies, Diagnostic Criteria in Autoimmune Diseases, and many more. However, a strange shift is now occurring in the world of immunology; renowned experts like Dr. Shoenfeld are pointing towards the potential effects of vaccine ingredients, specifically the toxic metal aluminum, on the immune system. In particular, these doctors issued new guidelines to identify the four categories of people who are most at risk for vaccine-induced autoimmunity.

Autoimmune disease results when the body’s immune system turns against the body and mistakenly attacks a non-threatening part of the body. For example, when the immune system erroneously attacks the conductive sheath around neurons, the damage leads to multiple sclerosis, or when autoantibodies target the islets of Langerhans in the pancreas, Type 1 diabetes results.

About four years ago, an article in the Journal of Autoimmunology first introduced ASIA (Autoimmune/Inflammatory Syndrome Induced by Adjuvants; also known as Shoenfeld’s syndrome), which is an umbrella term for a collection of symptoms, includingChronic Fatigue Syndrome. ASIA was found to appear after exposure to an adjuvant, which is an environmental agent. Since then, a massive amount of research has begun to reveal how common vaccine ingredients, particularly the metal aluminum, can be environmental toxins that trigger an immune system chain reaction in certain susceptible individuals. When this chain reaction runs its course, it may lead to ASIA and other cases of overt autoimmune disease.

“Throughout our lifetime, the normal immune system walks a fine line between preserving normal immune reactions and developing autoimmune diseases,” says the article. “The healthy immune system is tolerant to self-antigens. When self-tolerance is disturbed, dysregulation of the immune system follows, resulting in the emergence of an autoimmune disease. Vaccination is one of the conditions that may disturb this homeostasis in susceptible individuals, resulting in autoimmune phenomena and ASIA.”

As for what defines a “susceptible” individual, another paper titled “Predicting post-vaccination autoimmunity: Who might be at risk?,” lists four groups of people: 1) those who had an autoimmune reaction to a vaccine in the past, 2) those with an established medical history of autoimmunity, 3) those with a history of allergic reactions, and 4) those at high risk of developing autoimmune disease – either due to family medical history and/or the presence of autoantibodies that are detectable by blood tests or lifestyle factors, such as smoking and low vitamin D.

“Although data is limited,” Shoenfeld and his colleagues concluded, “it seems preferable that individuals with prior autoimmune or autoimmune-like reactions to vaccinations, should not be immunized, at least not with the same type of vaccine.”

Dr. Shoenfeld summarizes, “…many reports that describe post-vaccination autoimmunity strongly suggest that vaccines can indeed trigger autoimmunityDefined autoimmune diseases that may occur following vaccinations include arthritis, lupus (systemic lupus erythematosus, SLE), diabetes mellitus, thrombocytopenia, vasculitis, dermatomyositis, Guillain-Barre syndrome and demyelinating disordersAnd almost all types of vaccines have been reported to be associated with the onset of ASIA.”

 

 

Debate on vaccines and autoimmunity: Do not attack the author: discuss it methodologically

 

Nicola LuigiBragazziaAbdullaWatadbcdHowardAmitalbcdYehudaShoenfeldcd

https://doi.org/10.1016/j.vaccine.2017.08.018Get rights and content

https://www.sciencedirect.com/science/article/pii/S0264410X1731085X

Abstract

Since Jenner, vaccines and vaccinations have stirred a hot, highly polarized debate, leading to contrasting positions and feelings, ranging from acritical enthusiasm to blind denial. On the one hand, we find anti-vaccination movements which divulge and disseminate misleading information, myths, prejudices, and even frauds, with the main aim of denying that vaccination practices represent a major public health measure, being effective in controlling infectious diseases and safeguarding the wellbeing of entire communities. Recently, the authors of many vaccine safety investigations are being personally criticized rather than the actual science being methodologically assessed and critiqued. Unfortunately, this could result in making vaccine safety science a “hazardous occupation”. Critiques should focus on the science and not on the authors and on the scientists that publish reasonably high-quality science suggesting a problem with a given vaccine. These scientists require adequate professional protection so there are not disincentives to publish and to carry out research in the field. The issues for vaccine safety are not dissimilar to other areas such as medical errors and drug safety. 

Pharmacovigilance: the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug- or vaccine-related problem.

Medical Error: the failure of a planned action to be completed as intended or the use of a wrong plan to achieve an aim. The source of the error may be surgical, medical, drug-related or vaccine-related.

Adverse Drug or Vaccine Reaction: any noxious, unintended and undesired effect of a drug or vaccine that occurs at doses used for prevention, diagnosis and treatment.

Drug or Vaccine Toxicity: the capacity of a medication to cause acute and/or chronic injury to a human or pet by the administration of a drug or vaccine. The toxicity will vary according to the dosing or the way in which the toxic substance is administered (inhalation, ingestion, topical or injection [which can be subcutaneous, intravenous, intramuscular or intra-articular]). The toxicity of drugs and vaccines is often delayed and thus often goes recognized by either the patient, the patient’s loved ones or the inattentive or too-busy prescribing practitioner.

Combination Therapy: disease treatment with the simultaneous administration of two or more drugs or vaccines to 1) achieve efficacy with lower doses or lower toxicity; 2) gain additive or synergistic effects. Often the synergistic effects – especially in the case of intramuscularly-injected vaccines with aluminum and mercury additives in them – can actually multiply the neurotoxic effects of those two inherently toxic metals.

Antibodies: soluble immunoglobulin molecules that are generated by a body’s immune system in response to an antigen.

Autoimmunity: abnormal functioning of the immune system that causes an individual immune system to actual generate antibodies that attack their own body tissues Aluminum adjuvants are common causes of autoimmune disorders following some vaccines.

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Nat Rev Immunol. 2009 Apr;9(4):287-93. doi: 10.1038/nri2510.

Towards an Understanding of the Adjuvant Action of Aluminium.

Marrack P1, McKee ASMunks MW.

Abstract

The efficacy of vaccines depends on the presence of an adjuvant in conjunction with the antigen. Of these adjuvants, the ones that contain aluminium, which were first discovered empirically in 1926, are currently the most widely used. However, a detailed understanding of their mechanism of action has only started to be revealed. In this Timeline article, we briefly describe the initial discovery of aluminium adjuvants and discuss historically important advances. We also summarize recent progress in the field and discuss their implications and the remaining questions on how these adjuvants work.

 

BMC Medicine 2013, 11:99 - https://doi.org/10.1186/1741-7015-11-99

Slow CCL2-Dependent Translocation of Biopersistent Particles From Muscle to Brain

·       Zakir Khan, Christophe Combadière, François-Jérôme Authier, Valérie Itier, François Lux, Christopher Exley, Meriem Mahrouf-Yorgov, Xavier Decrouy, Philippe Moretto, Olivier Tillement, Romain K Gherardi, and Josette Cadusseau†

Abstract

Background

Long-term biodistribution of nanomaterials used in medicine is largely unknown. This is the case for alum, the most widely used vaccine adjuvant, which is a nanocrystalline compound spontaneously forming micron/submicron-sized agglomerates. Although generally well tolerated, alum is occasionally detected within monocyte-lineage cells long after immunization in presumably susceptible individuals with systemic/neurologic manifestations or autoimmune (inflammatory) syndrome induced by adjuvants (ASIA).

Methods

On the grounds of preliminary investigations in 252 patients with alum-associated ASIA showing both a selective increase of circulating CCL2, the major monocyte chemoattractant, and a variation in the CCL2 gene, we designed mouse experiments to assess biodistribution of vaccine-derived aluminum and of alum-particle fluorescent surrogates injected in muscle. Aluminum was detected in tissues by Morin stain and particle induced X-ray emission) (PIXE) Both 500 nm fluorescent latex beads and vaccine alum agglomerates-sized nanohybrids (Al-Rho) were used.

Results

Intramuscular injection of alum-containing vaccine was associated with the appearance of aluminum deposits in distant organs, such as spleen and brain where they were still detected one year after injection. Both fluorescent materials injected into muscle translocated to draining lymph nodes (DLNs) and thereafter were detected associated with phagocytes in blood and spleen. Particles linearly accumulated in the brain up to the six-month endpoint; they were first found in perivascular CD11b+ cells and then in microglia and other neural cells. DLN ablation dramatically reduced the biodistribution. Cerebral translocation was not observed after direct intravenous injection, but significantly increased in mice with chronically altered blood-brain-barrier. Loss/gain-of-function experiments consistently implicated CCL2 in systemic diffusion of Al-Rho particles captured by monocyte-lineage cells and in their subsequent neurodelivery. Stereotactic particle injection pointed out brain retention as a factor of progressive particle accumulation.

Conclusion

Nanomaterials can be transported by monocyte-lineage cells to DLNs, blood and spleen, and, similarly to HIV, may use CCL2-dependent mechanisms to penetrate the brain. This occurs at a very low rate in normal conditions explaining good overall tolerance of alum despite its strong neurotoxic potential. However, continuously escalating doses of this poorly biodegradable adjuvant in the population may become insidiously unsafe, especially in the case of over-immunization or immature/altered blood brain barrier or high constitutive CCL-2 production.

 

 

Pharmacol Res. 2015 Feb;92:18-22. doi: 10.1016/j.phrs.2014.08.002. Epub 2014 Sep 30.

Predicting Post-Vaccination Autoimmunity: Who Might be at Risk?

Soriano ANesher GShoenfeld Y

Abstract

Vaccinations have been used as an essential tool in the fight against infectious diseases, and succeeded in improving public health. However, adverse effects, including autoimmune conditions may occur following vaccinations (autoimmune/inflammatory syndrome induced by adjuvants--ASIA syndrome).

It has been postulated that autoimmunity could be triggered or enhanced by the vaccine immunogen contents, as well as by adjuvants, which are used to increase the immune reaction to the immunogen. Fortunately, vaccination-related ASIA is uncommon. Yet, by defining individuals at risk we may further limit the number of individuals developing post-vaccination ASIA.

In this perspective we defined four groups of individuals who might be susceptible to develop vaccination-induced ASIA:

1. patients with prior post-vaccination autoimmune phenomena; 

2. patients with a medical history of autoimmunity; 

3.  patients with a history of allergic reactions; and 

4. individuals who are prone to develop autoimmunity (having a family history of autoimmune diseases; asymptomatic carriers of autoantibodies; carrying certain genetic profiles, etc.).

 

 

J Autoimmun. 2011 Feb;36(1):4-8

'ASIA' - Autoimmune/Inflammatory Syndrome Induced by Adjuvants.

Shoenfeld YAgmon-Levin N.

Abstract

The role of various environmental factors in the pathogenesis of immune mediated diseases is well established. Of which, factors entailing an immune adjuvant activity such as infectious agents, silicone, aluminium salts and others were associated with defined and non-defined immune mediated diseases both in animal models and in humans. In recent years, four conditions: siliconosis, the Gulf war syndrome (GWS), the macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena were linked with previous exposure to an adjuvant. Furthermore, these four diseases share a similar complex of signs and symptoms which further support a common denominator. Thus, we review herein the current data regarding the role of adjuvants in the pathogenesis of immune mediated diseases as well as the amassed data regarding each of these four conditions. Relating to the current knowledge we would like to suggest including these comparable conditions under a common syndrome entitled ASIA, "Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants".

 

 

Immunol Res. 2013 Jul;56(2-3):304-16. doi: 10.1007/s12026-013-8403-1

Aluminum in the Central Nervous System (CNS): Toxicity in Humans and Animals, Vaccine Adjuvants, and Autoimmunity.

Shaw CATomljenovic L.

Abstract

We have examined the neurotoxicity of aluminum in humans and animals under various conditions, following different routes of administration, and provide an overview of the various associated disease states. The literature demonstrates clearly negative impacts of aluminum on the nervous system across the age span. In adults, aluminum exposure can lead to apparently age-related neurological deficits resembling Alzheimer's and has been linked to this disease and to the Guamanian variant, ALS-PDC. Similar outcomes have been found in animal models. In addition, injection of aluminum adjuvants in an attempt to model Gulf War syndrome and associated neurological deficits leads to an ALS phenotype in young male mice. In young children, a highly significant correlation exists between the number of pediatric aluminum-adjuvanted vaccines administered and the rate of autism spectrum disorders. Many of the features of aluminum-induced neurotoxicity may arise, in part, from autoimmune reactions, as part of the ASIA syndrome.

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J Immunotoxicol. 2013 Apr-Jun;10(2):210-22

How Aluminum Adjuvants Could Promote and Enhance Non-Target IgE Synthesis in a Genetically-Vulnerable Sub-Population.

Terhune TDDeth RC.

Abstract

Aluminum-containing adjuvants increase the effectiveness of vaccination, but their ability to augment immune responsiveness also carries the risk of eliciting non-target responses, especially in genetically susceptible individuals. This study reviews the relevant actions of aluminumadjuvants and sources of genetic risk that can combine to adversely affect a vulnerable sub-population.

Aluminum adjuvants promote oxidative stress and increase inflammasome activity, leading to the release of IL-1β, IL-18, and IL-33, but not the important regulatory cytokine IL-12. In addition, they stimulate macrophages to produce PGE₂, which also has a role in regulating immune responses. 

This aluminum-induced cytokine context leads to a T(H)2 immune response, characterized by the further release of IL-3, IL-4, IL-5, IL-9, IL-13, andIgE-potentiating factors such as sCD23. Genetic variants in cytokine genes, such as IL-4, IL-13, IL-33, and IL-18 influence the response to vaccines in children and are also associated with atopy. These genetic factors may therefore define a genetically-vulnerable sub-population, children with a family history of atopy, who may experience an exaggerated T(H)2 immune response to aluminum-containing vaccines. IL-4, sCD23, and IgE are common factors for both atopy and the immune-stimulating properties of aluminum adjuvants. IL-4 is critical in the production of IgE and total IgE up-regulation. IL-4 has also been reported to induce the production of sCD23 and trigger resting sIgM+, sIgD+ B-cells to switch to sIgE+ B-cells, making them targets for IgE-potentiating factors. Further, the actions of IgE-potentiating factors on sIgE+ B-cells are polyclonal and unrestricted, triggering their differentiation into IgE-forming plasma cells. 

These actions provide a mechanism for aluminum-adjuvant promotion and enhancement of non-target IgE in a genetically vulnerable sub-population.

Identification of these individuals may decrease the risk of adverse events associated with the use of aluminum-containing vaccines.

 

 

Ann N Y Acad Sci. 2006 Jun;1069:322-45.

Predicting and preventing autoimmunity, myth or reality?

Harel MShoenfeld Y.

Abstract

Many autoimmune diseases are chronic conditions that progress over the course of years and are characterized by the presence of autoantibodies that precede the overt disease by months or years.

As examples, the presence of two islet cell antibodies (ICA) are associated with a 50% risk of developing diabetes mellitus in 5 years; anticyclic citrullinated (anti-CCP) antibodies are found in the sera of rheumatoid arthritis (RA) patients a median of 4.5 years before the overt disease, and in systemic lupus erythematosus (SLE), patients accrue antibodies throughout a foreseen course during the 3-4 years prior to the clinical symptoms. This ability to predict autoimmune diseases, or rather their clinical manifestations, leads to the prospect of screening healthy individuals for autoantibodies.

The importance of such a notion lies not only in the ability to prevent life-threatening manifestations, such as Addisonian's crisis and thyroid storm, but also in the ability to treat and even prevent overt autoimmune diseases.

Among such documented treatment modalities are administration of aspirin in antiphospholipid syndrome, ursodeoxycholic acid in primary biliary cirrhosis (PBC), vitamin D in SLE and autoimmune thyroid diseases (AITD), and more. Although additional studies are still needed to fully assess these notions, as well as the appropriate screening strategies to apply them, one cannot ignore the prospect of predicting and preventing autoimmunity.

 

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Dr Kohls is a retired family physician from Duluth, MN, USA. Since his retirement from his holistic mental health practice he has been writing his weekly Duty to Warn column for the Duluth Reader, northeast Minnesota’s alternative newsweekly magazine. His columns, which are re-published around the world, deal with the dangers of American fascism, corporatism, militarization, racism, xenophobia, malnutrition, sea level rise, global warming, geo-engineering, solar radiation management, Big Copper Mining’s conscienceless exploitation of northeast Minnesota’s water-rich environment, Big Medicine’s over-screening, over-diagnosing, over-treating, Big Pharma’s over-drugging and Big Vaccine’s over-vaccination agendas (particularly of tiny infants), as well as other movements that threaten human health, the environment, democracy, civility and the sustainability of life on earth.  Many of his columns have been archived at a number of websites, including these four: http://duluthreader.com/search?search_term=Duty+to+Warn&p=2; http://www.globalresearch.ca/author/gary-g-kohlshttp://freepress.org/geographic-scope/national; and https://www.transcend.org/tms/search/?q=gary+kohls+articles